Current Partnering releases its first update of the article previously published last year on the most partnered therapeutic trends in pharma. The article analyses the most partnered therapeutic targets of 2009-2014 and identifies the areas that have gained in popularity since last year and the new areas that have entered the list.
The study was conducted by analysing the number of partnering deals by therapy area from 2009 – 2014 listed at Current Agreements, a leading deals and alliances database for the life sciences.
The following figure provides a top level overview of partnering activity based on broad therapeutic areas. Our database reveals that the top three most partnered therapeutic areas are oncology, infective diseases and hospital care.
Figure 1: Partnering trends by therapy area 2009-2014
Source:Current Partnering, 2014
The data in this article is extracted from our recently updated report Trends in Therapeutic Partnering
This article reviews the top 15 specific therapeutic targets based on most partnering deals announced.
Not surprisingly the list is dominated by chronic and life threatening conditions, many of which present in later stages of life. Examples include numerous cancers, infective diseases and other chronic later life conditions.
These therapeutic areas represent an attractive opportunity and unmet need for many big pharma and big biotech companies.
As a result, the deal making in these therapy areas is dominated by top pharma/biotech companies in-licensing from smaller companies in return for upfront, milestone and royalty streams should product candidates make it to market.
In addition, there is increased activity between companies/academia for discovery research in these therapeutic areas.
The following is a countdown of the top 15 therapeutic areas in reverse order since 2009 to mid 2014. The list also compares how each therapy area fared with last year’s statistics.
Top 15 therapeutic areas countdown
#15. Colorectal cancer ↓ from #14 last year
Number of deals announced 2009 to June 2014: 185
Number of deals announced 2007 to June 2013: 206
Deal dollars announced 2009 to June 2014: $1.75 billion
Deal dollars announced 2007 to June 2013: $1.99 billion
Colorectal cancer deal frequency
Source:Current Partnering, 2014
Colorectal cancer partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Colorectal Cancer Partnering 2009-2014
#14. Parkinson’s disease ↑ from #17 last year
Number of deals announced 2009 to June 2014: 195
Number of deals announced 2007 to June 2013: 203
Deal dollars announced 2009 to June 2014: $7.39 billion
Deal dollars announced 2007 to June 2013: $9.13 billion
Parkinson’s disease deal frequency
Source:Current Partnering, 2014
Parkinson’s disease partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Parkinson’s Disease Partnering 2009-2014
#13. Solid Tumor ↑ from #15 last year
Number of deals announced 2009 to June 2014: 197
Number of deals announced 2007 to June 2013: 193
Deal dollars announced 2009 to June 2014: $10.17 billion
Deal dollars announced 2007 to June 2013: $10.4 billion
Solid Tumor deal frequency
Source:Current Partnering, 2014
Solid Tumor partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Solid Tumor Partnering 2009 -2014
#12. Nutrition & Vitamins ↔ same position as last year
Number of deals announced 2009 to June 2014: 198
Number of deals announced 2007 to June 2013: 234
Deal dollars announced 2009 to June 2014: $13.51 billion
Deal dollars announced 2007 to June 2013: $13.94 billion
Nutrition & Vitamins deal frequency
Source:Current Partnering, 2014
Nutrition & Vitamins partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only:Nutrition & Vitamins Partnering 2009 - 2014
#11. Leukemia ↓ from #10 last year
Number of deals announced 2009 to June 2014: 211
Number of deals announced 2007 to June 2013: 254
Deal dollars announced 2009 to June 2014: $13.03 billion
Deal dollars announced 2007 to June 2013: $11.75 billion
Leukemia deal frequency
Source:Current Partnering, 2014
Leukemia partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only:Leukemia Partnering 2009-2014
#10. Prostate cancer ↑ from #11 last year
Number of deals announced 2009 to June 2014: 213
Number of deals announced 2007 to June 2013: 238
Deal dollars announced 2009 to June 2014: $6.13 billion
Deal dollars announced 2007 to June 2013: $4.83 billion
Prostate cancer deal frequency
Source:Current Partnering, 2014
Prostate cancer partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Prostate Cancer Partnering 2009-2014
#9. Influenza ↓ from #4 last year
Number of deals announced 2009 to June 2014: 226
Number of deals announced 2007 to June 2013: 332
Deal dollars announced 2009 to June 2014: $5.59 billion
Deal dollars announced 2007 to June 2013: $ 7.61billion
Influenza deal frequency
Source:Current Partnering, 2014
Influenza partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Influenza Partnering 2009-2014
#8. Inflammation ↓ from #7 last year
Number of deals announced 2009 to June 2014: 245
Number of deals announced 2007 to June 2013: 280
Deal dollars announced 2009 to June 2014: $12.56 billion
Deal dollars announced 2007 to June 2013: $6.98 billion
Inflammation deal frequency
Source:Current Partnering, 2014
Inflammation partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Inflammatory Partnering 2009-2014
#7. HIV ↓ from #5 last year
Number of deals announced 2009 to June 2014: 256
Number of deals announced 2007 to June 2013: 331
Deal dollars announced 2009 to June 2014: $4.24 billion
Deal dollars announced 2007 to June 2013: $5 billion
HIV deal frequency
Source:Current Partnering, 2014
HIV partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: HIV Partnering 2009-2014
#6. Wound healing ↑ from #9 last year
Number of deals announced 2009 to June 2014: 259
Number of deals announced 2007 to June 2013: 260
Deal dollars announced 2009 to June 2014: $0.95 billion
Deal dollars announced 2007 to June 2013: $1.65 billion
Wound healing deal frequency
Source:Current Partnering, 2014
Wound healing partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only:Wound healing Partnering 2009-2014
#5. Lung cancer ↑ from #8 last year
Number of deals announced 2009 to June 2014: 263
Number of deals announced 2007 to June 2013: 280
Deal dollars announced 2009 to June 2014: $5.50 billion
Deal dollars announced 2007 to June 2013: $ 6.54billion
Lung cancer deal frequency
Source:Current Partnering, 2014
Lung cancer partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Lung Cancer Partnering 2009-2014
#4. Alzheimer’s disease ↑ from #6 last year
Number of deals announced 2009 to June 2014: 282
Number of deals announced 2007 to June 2013: 292
Deal dollars announced 2009 to June 2014: $10.86 billion
Deal dollars announced 2007 to June 2013: $ 11.33billion
Alzheimer’s disease deal frequency
Source:Current Partnering, 2014
Alzheimer’s disease partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only:Alzheimer’s Disease Partnering 2009-2014
#3. Breast cancer ↔ same position as last year
Number of deals announced 2009 to June 2014: 328
Number of deals announced 2007 to June 2013: 332
Deal dollars announced 2009 to June 2014: $3.14 billion
Deal dollars announced 2007 to June 2013: $ 7.61billion
Breast cancer deal frequency
Source:Current Partnering, 2014
Breast cancer partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Breast Cancer Partnering 2009-2014
#2. Pain CNS ↔ same position as last year
Number of deals announced 2009 to June 2014: 380
Number of deals announced 2007 to June 2013: 480
Deal dollars announced 2009 to June 2014: $10.83 billion
Deal dollars announced 2007 to June 2013: $13.7billion
Pain CNS deal frequency
Source:Current Partnering, 2014
Pain CNS partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Pain Partnering 2009-2014
#1. Diabetes ↔ same position as last year
Number of deals announced 2009 to June 2014: 562
Number of deals announced 2007 to June 2013: 650
Deal dollars announced 2009 to June 2014: $26.94 billion
Deal dollars announced 2007 to June 2013: $ 36.72 billion
Diabetes deal frequency
Source:Current Partnering, 2014
Diabetes partnering by stage of development
Source:Current Partnering, 2014
To obtain comprehensive coverage of every deal announced:
- All 35 therapeutic areas: Trends in Therapeutic Partnering
- This therapeutic area only: Diabetes Partnering 2009-2014
Full list of top 35 therapeutic targets for partnering since 2009 can be found in the table of contents of the report: Trends in Therapeutic Partnering
- By Shamini Thiagarajan, for Current Partnering
Related
2013 Article: Top 15 Most Partnered Therapeutic Targets
Report: Trends in Therapeutic Partnering
View: Full list of therapeutic partnering reports
Report: Partnering Deals and Alliances with Big Pharma
Report: Partnering Deals and Alliances with Big Biotech
View: Current Partnering Insight Partnering Scorecard – view top life science partnering deals by value
View: Current Partnering’s Insight Deal Metrics – the latest deal trend infographics for life science deal making
View: Current Partnering’s Insight Big Pharma Deal Making Scorecard – latest trends in big pharma deal making activity
View: Current Partnering’s Insight Big Biotech Deal Making Scorecard – latest trends in big biotech deal making activity
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