Deals, Partnering

Collaboration agreement for INV102 (nadolol) and INV104 (zafirlukast)

Posted on 19 February 2014

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Invion announce a collaboration with 3M Drug Delivery Systems for the development of its inhaled respiratory drug franchise.

Invion’s agreement with 3M Drug Delivery Systems will assess the feasibility of inhaled versions of its two respiratory drug assets - INV102 (nadolol) and INV104 (zafirlukast) - delivered using 3M’s proprietary pressurized metered dose inhalation technology.

It will also enable manufacture for toxicology, and subsequently phase I studies, under an Invion-sponsored Investigational New Drug application, with the US Food and Drug Administration.

INV102 (nadolol) - a beta blocker currently used to treat high blood pressure and migraine, which is being repurposed by Invion to treat chronic inflammatory airway diseases, including moderate to severe asthma, COPD and cystic fibrosis.

INV104 (zafirlukast) - a leukotriene receptor antagonist (LTRA) which works by blocking the action of leukotrienes in the lungs, thereby preventing inflammation and narrowing of the airways.

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