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Xention and Servier pharma partners for XEN-D0103

Posted on 03 October 2013

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XENTION and SERVIER pharma partners by entering into a multi-year agreement for the development and commercialisation of XEN-D0103, a selective Kv1.5 modulator discovered and developed by Xention for the treatment of atrial fibrillation .

Under the terms of the agreement, Servier has received an option to acquire certain intellectual property rights and to further develop and commercialise XEN-D0103 in all territories except the USA and Japan.

All rights in the USA and Japan will be retained by Xention.

During the option period, the pharma partnerswill undertake a joint programme of clinical development of XEN-D0103 undertaking two phase 2 clinical studies aimed at demonstrating the efficacy of XEN-D0103 in reducing AF burden in paroxysmal AF.

In addition to an upfront fee, Servier will pay an option fee as well as a series of milestones totalling €120 million.

When Servier exercises its option, it will be responsible for the further clinical development and commercialisation of XEN-D0103 within its territories.

XEN-D0103 is a potent and selective blocker of Kv1.5, a potassium channel expressed in the atria, which represents an exciting new target for atrial fibrillation.

For further deal information visit Current Agreements (subscription required)


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