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Genzyme in biotech deals with AskBio for gene therapy licensing

Posted on 17 July 2013

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Genzyme biotech deals AskBio in a licensing agreement for duplex gene therapy vector technology. 

Asklepios BioPharmaceutical has entered into a non-exclusive cross-license biotech deals agreement with Genzyme, a big pharma company.

As part of the biotech deals, Genzyme will receive rights to AskBio’s Duplex gene therapy vector technology for its internal product development and external sublicensing.

AskBio’s Duplex vector technology allows a gene therapy Adeno-Associated Viral vector to package and deliver more potent therapeutic DNA cargo to a patient’s cells.

The Duplex vectors have been shown to bypass an intracellular-synthesis step necessary for converting a single-stranded DNA genome into a double-stranded genome.

This advancement results in faster onset and higher levels of gene expression.

Genzyme plans to use the Duplex vector technology, from the biotech deals, for its internal product development research.

Additionally under this biotech deals agreement, AskBio receives rights to Genzyme’s Intra-Strand Base-Pairing technology, which also supports packaging of DNA double-stranded genomes within an AAV-based gene therapy vector.


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