Big biotech, Biotech

Galapagos in $3.09 million funding from Flemish agency for Innovation by Science and Technology for psoriasis research

Posted on 09 July 2013

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Galapagos has been awarded a EUR2.4 million transformational medical research grant from the Flemish agency for Innovation by Science and Technology IWT for psoriasis research and development.

The goal of the funding for this 4-year project is to bring a novel mode of action compound into the clinic that might lead to a safe and effective treatment for patients suffering from psoriasis.

Psoriasis is a common skin disease with a high impact on well-being and for which options for patient are currently limited.

Psoriasis is a chronic disease, affecting approximately 3% of the population.

It has no final cure and therefore represents a high burden to quality of life.

Galapagos has discovered a compound series which presents a novel mode of action in psoriasis, which will be further developed using the funding.

This 4-year IWT funding will allow Galapagos, a big biotech, to explore the potential application of this compound series in disease models for psoriasis, both in preclinical systems as well as in a clinical setting.

After the discovery phase, Galapagos will initiate clinical trials with this innovative, oral compound for psoriasis by using an adaptive trial design, with the aim of achieving an efficiency gain in development costs and timelines, using the funding.

In the clinic, pharmacodynamic assessments will be evaluated in healthy volunteers by mimicking inflammation characteristics in a Proof-of-Mechanism study.

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Report: Psoriasis Partnering

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