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Genentech pharma delas Immunocore for $330 million cancer and viral targets

Posted on 28 June 2013

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Immunocore has entered into pharma deals involving a collaborative R&D and licensing agreement with Genentech for the discovery and development of multiple novel cancer targets using Immunocore’s ImmTAC technology.

Genentech, the big pharma and big biotech company taking part in the pharma deals, is a member of the Roche Group,

Under the terms of the pharma deals agreement, Immunocore will receive an initiation fee of between $10 and $20 million per programme and is eligible to receive in excess of $300 million in development and commercial milestone payments for each target programme and significant tiered royalties as part of the pharma deals.

Immunocore has created a world-leading platform of bi-specific biological drugs, called ImmTACs, which exploit the power of T Cell Receptors to recognise intracellular changes that occur during cancer or viral infection, which will be utilised in the pharma deals.

This unique recognition ability of TCRs sets them apart from traditional antibody-based therapies that can only recognise changes on the surface of cells, and provides, for the first time, the ability to develop extremely potent targeted therapies for cancers that are currently poorly served.

A particular feature is that the ImmTACs, to be used in the pharma deals, can be directed to target and destroy only the cancerous cells, avoiding damage to healthy cells.

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