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SciClone Pharmaceuticals big biotech deals Taiwan Liposome Company for ProFlow license

Posted on 26 June 2013

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SciClone Pharmaceuticals enters biotech deals with Taiwan Liposome granting SciClone a licensing and exclusive rights in China, Hong Kong and Macau to promote, market, distribute and sell ProFlow.

As part of the biotech deals, ProFlow is for the treatment of peripheral arterial disease and other indications.

ProFlow is a novel lipid emulsion-based formulation of prostaglandin E1, a vasodilator and platelet inhibitor.

TLC's proprietary lipid-based delivery systems are designed to modify and broaden the use of existing drugs and enhance their therapeutic index.

ProFlow has demonstrated to have twice the shelf life as currently marketed lipid emulsion formulations of PGE1.

A patent providing broad protection for ProFlow has been granted in China, Japan and Taiwan for the biotech deals.

TLC has also applied for worldwide composition of matter patents.

Under the terms of the biotech deals, TLC will be responsible for the continued development, including potential clinical trials and regulatory activities, as well as the manufacturing and supply of ProFlow, and SciClone will be responsible for all aspects of commercialization, including pre- and post-launch activities.

Financial terms of the biotech deals include clinical, regulatory and sales milestone payments up to an aggregate of $39.5 million.

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